Spontaneous remission in three cases of AML M5 with NPM1 mutation

Patients with NPM1-mutated AML M5 who develop spontaneous remission (SR) after antibiotic therapy at diagnosis seem to form a favorable prognosis and chemo sensitive subtype. We report three cases of AML M5 patients with the same genotype that experienced transient SR and are now leukemia free after...

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Detalles Bibliográficos
Autores principales: Camus, Vincent, Etancelin, Pascaline, Jardin, Fabrice, Lenain, Pascal, Contentin, Nathalie, Daliphard, Sylvie, Buchonnet, Gérard, Lemasle, Emilie, Lanic, Hélène, Leprêtre, Stéphane, Penther, Dominique, Dubois, Sydney, Tilly, Hervé, Bastard, Christian, Stamatoullas, Aspasia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641483/
https://www.ncbi.nlm.nih.gov/pubmed/26576281
http://dx.doi.org/10.1002/ccr3.408
Descripción
Sumario:Patients with NPM1-mutated AML M5 who develop spontaneous remission (SR) after antibiotic therapy at diagnosis seem to form a favorable prognosis and chemo sensitive subtype. We report three cases of AML M5 patients with the same genotype that experienced transient SR and are now leukemia free after standard treatment.

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