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AIF inhibits tumor metastasis by protecting PTEN from oxidation

Apoptosis-inducing factor (AIF) exerts dual roles on cell death and survival, but its substrates as a putative oxidoreductase and roles in tumorigenesis remain elusive. Here, we report that AIF physically interacts with and inhibits the oxidation of phosphatase and tensin homolog on chromosome ten (...

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Detalles Bibliográficos
Autores principales:	Shen, Shao-Ming, Guo, Meng, Xiong, Zhong, Yu, Yun, Zhao, Xu-Yun, Zhang, Fei-Fei, Chen, Guo-Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641507/ https://www.ncbi.nlm.nih.gov/pubmed/26415504 http://dx.doi.org/10.15252/embr.201540536

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