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Topoisomerase 2 Alpha Cooperates with Androgen Receptor to Contribute to Prostate Cancer Progression

Overexpression of TOP2A is associated with risk of systemic progression in prostate cancer patients, and higher levels of TOP2A were found in hormone-resistant cases. To elucidate the mechanism by which high levels of TOP2A contribute to tumor progression we generated TOP2A overexpressing prostate c...

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Detalles Bibliográficos
Autores principales: Schaefer-Klein, J. L., Murphy, Stephen J., Johnson, Sarah H., Vasmatzis, George, Kovtun, Irina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641711/
https://www.ncbi.nlm.nih.gov/pubmed/26560244
http://dx.doi.org/10.1371/journal.pone.0142327