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Xeroderma Pigmentosum Group A Suppresses Mutagenesis Caused by Clustered Oxidative DNA Adducts in the Human Genome
Clustered DNA damage is defined as multiple sites of DNA damage within one or two helical turns of the duplex DNA. This complex damage is often formed by exposure of the genome to ionizing radiation and is difficult to repair. The mutagenic potential and repair mechanisms of clustered DNA damage in...
Autores principales: | Sassa, Akira, Kamoshita, Nagisa, Kanemaru, Yuki, Honma, Masamitsu, Yasui, Manabu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641734/ https://www.ncbi.nlm.nih.gov/pubmed/26559182 http://dx.doi.org/10.1371/journal.pone.0142218 |
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