Cargando…

Colon Transit Time May Predict Inadequate Bowel Preparation in Patients With Chronic Constipation

BACKGROUND/AIMS: We evaluated whether colonic transit time (CTT) can predict the degree of bowel preparation in patients with chronic constipation undergoing scheduled colonoscopy in order to assist in the development of better bowel preparation strategies for these patients. METHODS: We analyzed th...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Hong Jun, Chae, Myeong Hun, Kim, Hyun-Soo, Kim, Jae Woo, Kim, Moon Young, Baik, Soon Koo, Kwon, Sang Ok, Kim, Hee Man, Lee, Kyong Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association for the Study of Intestinal Diseases 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641861/
https://www.ncbi.nlm.nih.gov/pubmed/26576140
http://dx.doi.org/10.5217/ir.2015.13.4.339
_version_ 1782400254097752064
author Park, Hong Jun
Chae, Myeong Hun
Kim, Hyun-Soo
Kim, Jae Woo
Kim, Moon Young
Baik, Soon Koo
Kwon, Sang Ok
Kim, Hee Man
Lee, Kyong Joo
author_facet Park, Hong Jun
Chae, Myeong Hun
Kim, Hyun-Soo
Kim, Jae Woo
Kim, Moon Young
Baik, Soon Koo
Kwon, Sang Ok
Kim, Hee Man
Lee, Kyong Joo
author_sort Park, Hong Jun
collection PubMed
description BACKGROUND/AIMS: We evaluated whether colonic transit time (CTT) can predict the degree of bowel preparation in patients with chronic constipation undergoing scheduled colonoscopy in order to assist in the development of better bowel preparation strategies for these patients. METHODS: We analyzed the records of 160 patients with chronic constipation from March 2007 to November 2012. We enrolled patients who had undergone a CTT test followed by colonoscopy. We defined patients with a CTT ≥30 hours as the slow transit time (STT) group, and patients with a CTT <30 hours as the normal transit time (NTT) group. Boston Bowel Preparation Scale (BBPS) scores were compared between the STT and NTT groups. RESULTS: Of 160 patients with chronic constipation, 82 (51%) were included in the STT group and 78 (49%) were included in the NTT group. Patients with a BBPS score of <6 were more prevalent in the STT group than in the NTT group (31.7% vs. 10.3%, P=0.001). Multivariate analysis showed that slow CTT was an independent predictor of inadequate bowel preparation (odds ratio, 0.261; 95% confidence interval, 0.107-0.634; P=0.003). The best CTT cut-off value for predicting inadequate bowel preparation in patients with chronic constipation was 37 hours, as determined by receiver operator characteristic (ROC) curve analysis (area under the ROC curve: 0.676, specificity: 0.735, sensitivity: 0.643). CONCLUSIONS: Patients with chronic constipation and a CTT >30 hours were at risk for inadequate bowel preparation. CTT measured prior to colonoscopy could be useful for developing individualized strategies for bowel preparation in patients with slow CTT, as these patients are likely to have inadequate bowel preparation.
format Online
Article
Text
id pubmed-4641861
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Korean Association for the Study of Intestinal Diseases
record_format MEDLINE/PubMed
spelling pubmed-46418612015-11-16 Colon Transit Time May Predict Inadequate Bowel Preparation in Patients With Chronic Constipation Park, Hong Jun Chae, Myeong Hun Kim, Hyun-Soo Kim, Jae Woo Kim, Moon Young Baik, Soon Koo Kwon, Sang Ok Kim, Hee Man Lee, Kyong Joo Intest Res Original Article BACKGROUND/AIMS: We evaluated whether colonic transit time (CTT) can predict the degree of bowel preparation in patients with chronic constipation undergoing scheduled colonoscopy in order to assist in the development of better bowel preparation strategies for these patients. METHODS: We analyzed the records of 160 patients with chronic constipation from March 2007 to November 2012. We enrolled patients who had undergone a CTT test followed by colonoscopy. We defined patients with a CTT ≥30 hours as the slow transit time (STT) group, and patients with a CTT <30 hours as the normal transit time (NTT) group. Boston Bowel Preparation Scale (BBPS) scores were compared between the STT and NTT groups. RESULTS: Of 160 patients with chronic constipation, 82 (51%) were included in the STT group and 78 (49%) were included in the NTT group. Patients with a BBPS score of <6 were more prevalent in the STT group than in the NTT group (31.7% vs. 10.3%, P=0.001). Multivariate analysis showed that slow CTT was an independent predictor of inadequate bowel preparation (odds ratio, 0.261; 95% confidence interval, 0.107-0.634; P=0.003). The best CTT cut-off value for predicting inadequate bowel preparation in patients with chronic constipation was 37 hours, as determined by receiver operator characteristic (ROC) curve analysis (area under the ROC curve: 0.676, specificity: 0.735, sensitivity: 0.643). CONCLUSIONS: Patients with chronic constipation and a CTT >30 hours were at risk for inadequate bowel preparation. CTT measured prior to colonoscopy could be useful for developing individualized strategies for bowel preparation in patients with slow CTT, as these patients are likely to have inadequate bowel preparation. Korean Association for the Study of Intestinal Diseases 2015-10 2015-10-15 /pmc/articles/PMC4641861/ /pubmed/26576140 http://dx.doi.org/10.5217/ir.2015.13.4.339 Text en © Copyright 2015. Korean Association for the Study of Intestinal Diseases. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Park, Hong Jun
Chae, Myeong Hun
Kim, Hyun-Soo
Kim, Jae Woo
Kim, Moon Young
Baik, Soon Koo
Kwon, Sang Ok
Kim, Hee Man
Lee, Kyong Joo
Colon Transit Time May Predict Inadequate Bowel Preparation in Patients With Chronic Constipation
title Colon Transit Time May Predict Inadequate Bowel Preparation in Patients With Chronic Constipation
title_full Colon Transit Time May Predict Inadequate Bowel Preparation in Patients With Chronic Constipation
title_fullStr Colon Transit Time May Predict Inadequate Bowel Preparation in Patients With Chronic Constipation
title_full_unstemmed Colon Transit Time May Predict Inadequate Bowel Preparation in Patients With Chronic Constipation
title_short Colon Transit Time May Predict Inadequate Bowel Preparation in Patients With Chronic Constipation
title_sort colon transit time may predict inadequate bowel preparation in patients with chronic constipation
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641861/
https://www.ncbi.nlm.nih.gov/pubmed/26576140
http://dx.doi.org/10.5217/ir.2015.13.4.339
work_keys_str_mv AT parkhongjun colontransittimemaypredictinadequatebowelpreparationinpatientswithchronicconstipation
AT chaemyeonghun colontransittimemaypredictinadequatebowelpreparationinpatientswithchronicconstipation
AT kimhyunsoo colontransittimemaypredictinadequatebowelpreparationinpatientswithchronicconstipation
AT kimjaewoo colontransittimemaypredictinadequatebowelpreparationinpatientswithchronicconstipation
AT kimmoonyoung colontransittimemaypredictinadequatebowelpreparationinpatientswithchronicconstipation
AT baiksoonkoo colontransittimemaypredictinadequatebowelpreparationinpatientswithchronicconstipation
AT kwonsangok colontransittimemaypredictinadequatebowelpreparationinpatientswithchronicconstipation
AT kimheeman colontransittimemaypredictinadequatebowelpreparationinpatientswithchronicconstipation
AT leekyongjoo colontransittimemaypredictinadequatebowelpreparationinpatientswithchronicconstipation