Cargando…
PPARα Is Required for PPARδ Action in Regulation of Body Weight and Hepatic Steatosis in Mice
Peroxisome proliferator activated receptors alpha (PPARα) and delta (PPARδ) belong to the nuclear receptor superfamily. PPARα is a target of well established lipid-lowering drugs. PPARδ (also known as PPARβ/δ) has been investigated as a promising antidiabetic drug target; however, the evidence in th...
Autores principales: | Garbacz, Wojciech G., Huang, Jeffrey T. J., Higgins, Larry G., Wahli, Walter, Palmer, Colin N. A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641930/ https://www.ncbi.nlm.nih.gov/pubmed/26604919 http://dx.doi.org/10.1155/2015/927057 |
Ejemplares similares
-
Conditional Expression of Human PPARδ and a Dominant Negative Variant of hPPARδ In Vivo
por: Higgins, Larry G., et al.
Publicado: (2012) -
Insights into the Role of PPARβ/δ in NAFLD
por: Chen, Jiapeng, et al.
Publicado: (2018) -
Ligand Modulated Antagonism of PPARγ by Genomic and Non-Genomic Actions of PPARδ
por: Gustafsson, Mattias C. U., et al.
Publicado: (2009) -
The Effect of PPARα, PPARδ, PPARγ, and PPARpan Agonists on Body Weight, Body Mass, and Serum Lipid Profiles in Diet-Induced Obese AKR/J Mice
por: Harrington, W. Wallace, et al.
Publicado: (2007) -
The PPARβ/δ-AMPK Connection in the Treatment of Insulin Resistance
por: Aguilar-Recarte, David, et al.
Publicado: (2021)