Sphingosine-1-Phosphate and Its Receptors: A Mutual Link between Blood Coagulation and Inflammation

Sphingosine-1-phosphate (S1P) is a versatile lipid signaling molecule and key regulator in vascular inflammation. S1P is secreted by platelets, monocytes, and vascular endothelial and smooth muscle cells. It binds specifically to a family of G-protein-coupled receptors, S1P receptors 1 to 5, resulti...

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Detalles Bibliográficos
Autores principales: Mahajan-Thakur, Shailaja, Böhm, Andreas, Jedlitschky, Gabriele, Schrör, Karsten, Rauch, Bernhard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641948/
https://www.ncbi.nlm.nih.gov/pubmed/26604433
http://dx.doi.org/10.1155/2015/831059

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