Plasma 24-metabolite Panel Predicts Preclinical Transition to Clinical Stages of Alzheimer’s Disease

We recently documented plasma lipid dysregulation in preclinical late-onset Alzheimer’s disease (LOAD). A 10 plasma lipid panel, predicted phenoconversion and provided 90% sensitivity and 85% specificity in differentiating an at-risk group from those that would remain cognitively intact. Despite the...

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Detalles Bibliográficos
Autores principales: Fiandaca, Massimo S., Zhong, Xiaogang, Cheema, Amrita K., Orquiza, Michael H., Chidambaram, Swathi, Tan, Ming T., Gresenz, Carole Roan, FitzGerald, Kevin T., Nalls, Mike A., Singleton, Andrew B., Mapstone, Mark, Federoff, Howard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642213/
https://www.ncbi.nlm.nih.gov/pubmed/26617567
http://dx.doi.org/10.3389/fneur.2015.00237

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