Inhibition of A20 expression in tumor microenvironment exerts anti-tumor effect through inducing myeloid-derived suppressor cells apoptosis

Myeloid-derived suppressor cells (MDSCs) are known to play important roles in the development of immunosuppressive tumor microenvironment. A20 is a zinc-finger protein which could negatively regulate apoptosis in several cell types. However, the role of A20 in tumor microenvironment remains largely...

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Detalles Bibliográficos
Autores principales: Shao, Bin, Wei, Xiawei, Luo, Min, Yu, Jiayun, Tong, Aiping, Ma, Xuelei, Ye, Tinghong, Deng, Hongxin, Sang, Yaxiong, Liang, Xiao, Ma, Yu, Wu, Qinjie, Du, Wei, Du, Jing, Gao, Xiang, Wen, Yi, Fu, Ping, Shi, Huashan, Luo, Shuntao, Wei, Yuquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642332/
https://www.ncbi.nlm.nih.gov/pubmed/26561336
http://dx.doi.org/10.1038/srep16437

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