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Protein receptor-independent plasma membrane remodeling by HAMLET: a tumoricidal protein-lipid complex
A central tenet of signal transduction in eukaryotic cells is that extra-cellular ligands activate specific cell surface receptors, which orchestrate downstream responses. This ‘’protein-centric” view is increasingly challenged by evidence for the involvement of specialized membrane domains in signa...
Autores principales: | Nadeem, Aftab, Sanborn, Jeremy, Gettel, Douglas L., James, Ho C. S., Rydström, Anna, Ngassam, Viviane N., Klausen, Thomas Kjær, Pedersen, Stine Falsig, Lam, Matti, Parikh, Atul N., Svanborg, Catharina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642337/ https://www.ncbi.nlm.nih.gov/pubmed/26561036 http://dx.doi.org/10.1038/srep16432 |
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