Reveromycin A Administration Prevents Alveolar Bone Loss in Osteoprotegerin Knockout Mice with Periodontal Disease

Chronic periodontal disease is characterized by alveolar bone loss and inflammatory changes. Reveromycin A (RMA) was recently developed and is a unique agent for inhibiting osteoclast activity. This study analysed the effects of RMA in an experimental mouse model of periodontitis involving osteoprot...

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Detalles Bibliográficos
Autores principales: Mizuno, Manami, Miyazawa, Ken, Tabuchi, Masako, Tanaka, Miyuki, Yoshizako, Mamoru, Minamoto, Chisato, Torii, Yasuyoshi, Tamaoka, Yusuke, Kawatani, Makoto, Osada, Hiroyuki, Maeda, Hatsuhiko, Goto, Shigemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642347/
https://www.ncbi.nlm.nih.gov/pubmed/26561427
http://dx.doi.org/10.1038/srep16510

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