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Regulation of iron homeostasis by the p53-ISCU pathway

Accumulation of iron in tissues increases the risk of cancer, but iron regulatory mechanisms in cancer tissues are largely unknown. Here, we report that p53 regulates iron metabolism through the transcriptional regulation of ISCU (iron-sulfur cluster assembly enzyme), which encodes a scaffold protei...

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Detalles Bibliográficos
Autores principales:	Funauchi, Yuki, Tanikawa, Chizu, Yi Lo, Paulisally Hau, Mori, Jinichi, Daigo, Yataro, Takano, Atsushi, Miyagi, Yohei, Okawa, Atsushi, Nakamura, Yusuke, Matsuda, Koichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642350/ https://www.ncbi.nlm.nih.gov/pubmed/26560363 http://dx.doi.org/10.1038/srep16497

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