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Synthesis and antitumor activity of novel N-substituted carbazole imidazolium salt derivatives

A series of novel N-substituted carbazole imidazolium salt derivatives has been prepared and investigated for their cytotoxic activity against five human tumor cell lines by MTS assay. The results indicated that the existence of 5,6-dimethyl-benzimidazole ring, substitution of the imidazolyl-3-posit...

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Detalles Bibliográficos
Autores principales: Liu, Lan-Xiang, Wang, Xue-Quan, Zhou, Bei, Yang, Li-Juan, Li, Yan, Zhang, Hong-Bin, Yang, Xiao-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642527/
https://www.ncbi.nlm.nih.gov/pubmed/26287982
http://dx.doi.org/10.1038/srep13101