TSC2 mediates hyperosmotic stress-induced inactivation of mTORC1

mTOR complex 1 (mTORC1) regulates cell growth and metabolism. mTORC1 activity is regulated via integration of positive growth-promoting stimuli and negative stress stimuli. One stress cells confront in physiological and pathophysiological contexts is hyperosmotic stress. The mechanism by which hyper...

Descripción completa

Detalles Bibliográficos
Autores principales: Plescher, Monika, Teleman, Aurelio A., Demetriades, Constantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642562/
https://www.ncbi.nlm.nih.gov/pubmed/26345496
http://dx.doi.org/10.1038/srep13828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642562/
https://www.ncbi.nlm.nih.gov/pubmed/26345496
http://dx.doi.org/10.1038/srep13828

Ejemplares similares