Cargando…

X-ray irradiation activates K(+) channels via H(2)O(2) signaling

Ionizing radiation is a universal tool in tumor therapy but may also cause secondary cancers or cell invasiveness. These negative side effects could be causally related to the human-intermediate-conductance Ca(2+)-activated-K(+)-channel (hIK), which is activated by X-ray irradiation and affects cell...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gibhardt, Christine S., Roth, Bastian, Schroeder, Indra, Fuck, Sebastian, Becker, Patrick, Jakob, Burkhard, Fournier, Claudia, Moroni, Anna, Thiel, Gerhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642570/ https://www.ncbi.nlm.nih.gov/pubmed/26350345 http://dx.doi.org/10.1038/srep13861

Ejemplares similares

X-ray irradiation triggers immune response in human T-lymphocytes via store-operated Ca(2+) entry and NFAT activation
por: Tandl, Dominique, et al.
Publicado: (2022)

Fast and slow gating are inherent properties of the pore module of the K(+) channel Kcv
por: Abenavoli, Alessandra, et al.
Publicado: (2009)

Ca(2+) block and flickering both contribute to the negative slope of the IV curve in BK channels
por: Schroeder, Indra, et al.
Publicado: (2013)

Distinct lipid bilayer compositions have general and protein-specific effects on K(+) channel function
por: Winterstein, Laura-Marie, et al.
Publicado: (2021)

Identification of Intrahelical Bifurcated H-Bonds as a New Type of Gate in K(+) Channels
por: Rauh, Oliver, et al.
Publicado: (2017)

The voltage-sensing domain of a phosphatase gates the pore of a potassium channel
por: Arrigoni, Cristina, et al.
Publicado: (2013)

Structural basis for ion selectivity in TMEM175 K(+) channels
por: Brunner, Janine D, et al.
Publicado: (2020)

Reconstitution and functional characterization of ion channels from nanodiscs in lipid bilayers
por: Winterstein, Laura-Marie, et al.
Publicado: (2018)

Asymmetric Interplay Between K(+) and Blocker and Atomistic Parameters From Physiological Experiments Quantify K(+) Channel Blocker Release
por: Gabriel, Tobias S., et al.
Publicado: (2021)

Inferring functional units in ion channel pores via relative entropy
por: Schmidt, Michael, et al.
Publicado: (2021)

A small viral potassium ion channel with an inherent inward rectification
por: Eckert, Denise, et al.
Publicado: (2019)

Effect of Cytosolic pH on Inward Currents Reveals Structural Characteristics of the Proton Transport Cycle in the Influenza A Protein M2 in Cell-Free Membrane Patches of Xenopus oocytes
por: DiFrancesco, Mattia L., et al.
Publicado: (2014)

Ionizing Radiation Induces Morphological Changes and Immunological Modulation of Jurkat Cells
por: Voos, Patrick, et al.
Publicado: (2018)

Light-Regulated Transcription of a Mitochondrial-Targeted K(+) Channel
por: Engel, Anja J., et al.
Publicado: (2020)

Anomalous X-ray diffraction studies of ion transport in K(+) channels
por: Langan, Patricia S., et al.
Publicado: (2018)

X-ray-irradiated K562 feeder cells for expansion of functional CAR-T cells
por: Bui, Khac Cuong, et al.
Publicado: (2022)

Weak Cation Selectivity in HCN Channels Results From K(+)-Mediated Release of Na(+) From Selectivity Filter Binding Sites
por: Bauer, Daniel, et al.
Publicado: (2022)

Long‐term stability of a 50‐kV X‐ray unit for stereotactic irradiation
por: Biggs, Peter J.
Publicado: (2006)

Sterility of Aedes albopictus by X-ray Irradiation as an Alternative to γ-ray Irradiation for the Sterile Insect Technique
por: Wang, Lin-Min, et al.
Publicado: (2023)

Effects of carbon ion irradiation and X-ray irradiation on the ubiquitylated protein accumulation
por: ISOZAKI, TETSURO, et al.
Publicado: (2016)

CADEM: calculate X-ray diffraction of epitaxial multilayers
por: Komar, Paulina, et al.
Publicado: (2017)

Acute response of pig skin to irradiation with $^{12}C$-ions or 200 kV X-rays
por: Zacharias, T, et al.
Publicado: (1997)

System and path planning algorithm for low‐kV X‐ray free‐form surface irradiation
por: Rothfuss, Andreas, et al.
Publicado: (2018)

X-ray crystallography of TRP channels
por: Singh, Appu K., et al.
Publicado: (2018)

Iodine containing porous organosilica nanoparticles trigger tumor spheroids destruction upon monochromatic X-ray irradiation: DNA breaks and K-edge energy X-ray
por: Higashi, Yuya, et al.
Publicado: (2021)

Effect of X-ray irradiation on ancient DNA in sub-fossil bones – Guidelines for safe X-ray imaging
por: Immel, Alexander, et al.
Publicado: (2016)

Radioprotection of mice by lactoferrin against irradiation with sublethal X-rays
por: Nishimura, Yoshikazu, et al.
Publicado: (2014)

Age-related effects of X-ray irradiation on mouse hippocampus
por: Casciati, Arianna, et al.
Publicado: (2016)

Changes in splenic uptake pattern associated with X-ray irradiation
por: de Faria, Fernando P., et al.
Publicado: (2020)

Organic phosphorescent scintillation from copolymers by X-ray irradiation
por: Gan, Nan, et al.
Publicado: (2022)

Recommendations for reducing exposure to medical X-ray irradiation (Review)
por: Shi, Hai-Min, et al.
Publicado: (2022)

Use of X-ray irradiation for inactivation of Aspergillus in cannabis flower
por: Frink, Stephen, et al.
Publicado: (2022)

cyclic AMP Regulation and Its Command in the Pacemaker Channel HCN4
por: Porro, Alessandro, et al.
Publicado: (2020)

Neutron and X-ray irradiation of silicon based Mach-Zehnder modulators
por: El Nasr-Storey, S S, et al.
Publicado: (2015)

Tip60 is associated with resistance to X‐ray irradiation in prostate cancer
por: Xie, Xin, et al.
Publicado: (2017)

Effect of X-ray irradiation on hepatocarcinoma cells and erythrocytes in salvaged blood
por: Zhang, Feng-Jiang, et al.
Publicado: (2017)

Biological X-ray irradiator characterization for use with small animals and cells
por: Bruno, A. Colello, et al.
Publicado: (2017)

Effect of X-ray irradiation on development, flight, and reproduction of Spodoptera litura
por: Jiang, Shan, et al.
Publicado: (2022)

Mating Competitiveness of Male Spodoptera frugiperda (Smith) Irradiated by X-rays
por: Jiang, Shan, et al.
Publicado: (2023)

Generation of bone marrow chimeras using X-ray irradiation: comparison to cesium irradiation and use in immunotherapy
por: Eng, Jason, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_4ie1b4emkejedv0nkm94nlob1s