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Myeloid-related protein 8 induces self-tolerance and cross-tolerance to bacterial infection via TLR4- and TLR2-mediated signal pathways
Myeloid-related protein 8 (Mrp8) is the active component of Mrp8/14 protein complex released by phagocytes at the site of infection and stimulates inflammatory responses. However, it is unclear whether Mrp8 could induce self-tolerance and cross-tolerance to bacterial infection. Here we report that M...
Autores principales: | Coveney, Andrew P., Wang, Wei, Kelly, Justin, Hua Liu, Jing, Blankson, Siobhan, Di Wu, Qiong, Paul Redmond, H., Huai Wang, Jiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642578/ https://www.ncbi.nlm.nih.gov/pubmed/26329314 http://dx.doi.org/10.1038/srep13694 |
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