Well-mixed plasma and tissue viral populations in RT-SHIV-infected macaques implies a lack of viral replication in the tissues during antiretroviral therapy

BACKGROUND: Determining the anatomic compartments that contribute to plasma HIV-1 is critical to understanding the sources of residual viremia during combination antiretroviral therapy (ART). We analyzed viral DNA and RNA populations in the plasma and tissues from macaques infected with SIV containi...

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Detalles Bibliográficos
Autores principales: Kearney, Mary F., Anderson, Elizabeth M., Coomer, Charles, Smith, Luke, Shao, Wei, Johnson, Nicholas, Kline, Christopher, Spindler, Jonathan, Mellors, John W., Coffin, John M., Ambrose, Zandrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642622/
https://www.ncbi.nlm.nih.gov/pubmed/26559632
http://dx.doi.org/10.1186/s12977-015-0212-2

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