Cargando…

Reversion of malignant phenotypes of human glioblastoma cells by β-elemene through β-catenin-mediated regulation of stemness-, differentiation- and epithelial-to-mesenchymal transition-related molecules

BACKGROUND: Glioblastoma is the most common and lethal type of primary brain tumor. β-Elemene, a natural plant drug extracted from Curcuma wenyujin, has shown strong anti-tumor effects in various tumors with low toxicity. However, the effects of β-elemene on malignant phenotypes of human glioblastom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Tingzhun, Li, Xiaoming, Luo, Lihan, Wang, Xiaogang, Li, Zhiqing, Xie, Peng, Gao, Xu, Song, Zhenquan, Su, Jingyuan, Liang, Guobiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642639/ https://www.ncbi.nlm.nih.gov/pubmed/26563263 http://dx.doi.org/10.1186/s12967-015-0727-2

Ejemplares similares

The reversal of antineoplastic drug resistance in cancer cells by β-elemene
por: Zhang, Guan-Nan, et al.
Publicado: (2015)

β-Elemene treatment of glioblastoma: a single-center retrospective study
por: Ma, Chunxiao, et al.
Publicado: (2016)

The critical role of EGF-β-catenin signaling in the epithelial-mesenchymal transition in human glioblastoma
por: Wang, Xingqiang, et al.
Publicado: (2017)

Therapeutic effects of β-elemene via attenuation of the Wnt/β-catenin signaling pathway in cervical cancer cells
por: Wang, Lufang, et al.
Publicado: (2018)

β-elemene combined with temozolomide in treatment of brain glioma
por: Zhang, Xiaomin, et al.
Publicado: (2021)

β-Elemene inhibits the proliferation of primary human airway granulation fibroblasts by down-regulating canonical Wnt/β-catenin pathway
por: Xue, Cheng, et al.
Publicado: (2018)

Drug delivery systems for elemene, its main active ingredient β-elemene, and its derivatives in cancer therapy
por: Zhai, Bingtao, et al.
Publicado: (2018)

Combinative treatment of β-elemene and cetuximab is sensitive to KRAS mutant colorectal cancer cells by inducing ferroptosis and inhibiting epithelial-mesenchymal transformation
por: Chen, Peng, et al.
Publicado: (2020)

β-Elemene Triggers ROS-dependent Apoptosis in Glioblastoma Cells Through Suppressing STAT3 Signaling Pathway
por: Cai, Shi-zhong, et al.
Publicado: (2021)

Raddeanin A inhibited epithelial-mesenchymal transition (EMT) and angiogenesis in glioblastoma by downregulating β-catenin expression
por: Wu, Bingshan, et al.
Publicado: (2021)

β-catenin activates TGF-β-induced epithelial–mesenchymal transition in adenomyosis
por: Yoo, Jung-Yoon, et al.
Publicado: (2020)

β-Elemene Inhibits the Proliferation and Migration of Human Glioblastoma Cell Lines via Suppressing Ring Finger Protein 135
por: Alizada, M, et al.
Publicado: (2020)

Loss of β-catenin in adrenocortical cancer cells causes growth inhibition and reversal of epithelial-to-mesenchymal transition
por: Salomon, Aude, et al.
Publicado: (2015)

Preparation, characterization, pharmacokinetics and anticancer effects of PEGylated β-elemene liposomes
por: Zhai, Bingtao, et al.
Publicado: (2020)

Asymmetric total synthesis of (1S,2S,4S)-β-elemene
por: Chen, Wei, et al.
Publicado: (2022)

FBP1 induced by β‐elemene enhances the sensitivity of gefitinib in lung cancer
por: Li, Jian, et al.
Publicado: (2022)

β-Elemene Promotes Apoptosis Induced by Hyperthermia via Inhibiting HSP70
por: Zhang, Cuiwei, et al.
Publicado: (2022)

Combinatorial Antitumor Effect of Rapamycin and β-Elemene in Follicular Thyroid Cancer Cells
por: Zhou, Jun, et al.
Publicado: (2016)

The Antitumor Efficacy of β-Elemene by Changing Tumor Inflammatory Environment and Tumor Microenvironment
por: Xie, Qiang, et al.
Publicado: (2020)

β-catenin in epithelial tumorigenesis
por: Lu, Tsai-Ling, et al.
Publicado: (2015)

Antitumor effects of β-elemene via targeting the phosphorylation of insulin receptor
por: Wu, Dawei, et al.
Publicado: (2018)

The Chemopreventive Role of β-Elemene in Cholangiocarcinoma by Restoring PCDH9 Expression
por: Wu, Qing, et al.
Publicado: (2022)

Dissolvable hyaluronic acid microneedles loaded with β-Elemene for the treatment of psoriasis
por: Wang, Chun, et al.
Publicado: (2022)

Combinative effects of β-elemene and propranolol on the proliferation, migration, and angiogenesis of hemangioma
por: Wang, Zhenyu, et al.
Publicado: (2023)

The mechanism of m(6)A methyltransferase METTL3-mediated autophagy in reversing gefitinib resistance in NSCLC cells by β-elemene
por: Liu, Shuiping, et al.
Publicado: (2020)

β-Elemene Suppresses Obesity-Induced Imbalance in the Microbiota-Gut-Brain Axis
por: Zhou, Yingyu, et al.
Publicado: (2021)

Sortilin promotes glioblastoma invasion and mesenchymal transition through GSK-3β/β-catenin/twist pathway
por: Yang, Wei, et al.
Publicado: (2019)

GOLPH3 induces epithelial–mesenchymal transition via Wnt/β‐catenin signaling pathway in epithelial ovarian cancer
por: Sun, Jing, et al.
Publicado: (2017)

Fucoxanthin induces apoptosis and reverses epithelial-mesenchymal transition via inhibiting Wnt/β-catenin pathway in lung adenocarcinoma
por: Luan, Heqi, et al.
Publicado: (2022)

β-Catenin/CBP–Dependent Signaling Regulates TGF-β–Induced Epithelial to Mesenchymal Transition of Lens Epithelial Cells
por: Taiyab, Aftab, et al.
Publicado: (2016)

The influence of astragalus polysaccharide and β-elemene on LX-2 cell growth, apoptosis and activation
por: Zheng, Jin, et al.
Publicado: (2014)

BYSL Promotes Glioblastoma Cell Migration, Invasion, and Mesenchymal Transition Through the GSK-3β/β-Catenin Signaling Pathway
por: Sha, Zhuang, et al.
Publicado: (2020)

Sirtuin 7 Promotes Mesenchymal to Epithelial Transition by β-Catenin Redistribution and Stabilization
por: Kiran, Shashi, et al.
Publicado: (2020)

The Role of E3 Ubiquitin Ligase Cbl Proteins in β-Elemene Reversing Multi-Drug Resistance of Human Gastric Adenocarcinoma Cells
por: Zhang, Ye, et al.
Publicado: (2013)

Anti-Lung-Cancer Activity and Liposome-Based Delivery Systems of β-Elemene
por: Chen, Meiwan, et al.
Publicado: (2012)

β-Elemene: Mechanistic Studies on Cancer Cell Interaction and Its Chemosensitization Effect
por: Jiang, Ziyu, et al.
Publicado: (2017)

Antiproliferative and apoptotic effects of β-elemene on human hepatoma HepG2 cells
por: Dai, Zhi-Jun, et al.
Publicado: (2013)

Budding uninhibited by benzimidazoles 1 promotes cell proliferation, invasion, and epithelial-mesenchymal transition via the Wnt/β-catenin signaling in glioblastoma
por: Zhang, Jinshi, et al.
Publicado: (2023)

SNX3 suppresses the migration and invasion of colorectal cancer cells by reversing epithelial-to-mesenchymal transition via the β-catenin pathway
por: Pan, Biran, et al.
Publicado: (2019)

β-Arrestin1 Promotes Colorectal Cancer Metastasis Through GSK-3β/β-Catenin Signaling- Mediated Epithelial-to-Mesenchymal Transition
por: Song, Qing, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_3gscvidssa24pjcog7vs9g0t50