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Central delivery of iodine-125–labeled cetuximab, etanercept and anakinra after perispinal injection in rats: possible implications for treating Alzheimer’s disease

INTRODUCTION: Alzheimer’s disease is a debilitating condition, and the search for an effective treatment is ongoing. Inflammation, in reaction to amyloid deposition, is thought to accelerate cognitive decline. With tumor necrosis factor α being an important proinflammatory cytokine, a recent trial i...

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Detalles Bibliográficos
Autores principales: Roerink, Megan E., Groen, Rob JM, Franssen, Gerben, Lemmers-van de Weem, Bianca, Boerman, Otto C., van der Meer, Jos WM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642641/
https://www.ncbi.nlm.nih.gov/pubmed/26560086
http://dx.doi.org/10.1186/s13195-015-0149-7