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Oxacillin sensitization of methicillin-resistant Staphylococcus aureus and methicillin-resistant Staphylococcus pseudintermedius by antisense peptide nucleic acids in vitro

BACKGROUND: Antibiotic resistance genes can be targeted by antisense agents, which can reduce their expression and thus restore cellular susceptibility to existing antibiotics. Antisense inhibitors can be gene and pathogen specific, or designed to inhibit a group of bacteria having conserved sequenc...

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Detalles Bibliográficos
Autores principales: Goh, Shan, Loeffler, Anette, Lloyd, David H., Nair, Sean P., Good, Liam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642645/
https://www.ncbi.nlm.nih.gov/pubmed/26560174
http://dx.doi.org/10.1186/s12866-015-0599-x