Cargando…

Immunological and short-term brain volume changes in relapsing forms of multiple sclerosis treated with interferon beta-1a subcutaneously three times weekly: an open-label two-arm trial

BACKGROUND: Brain volume atrophy is observed in relapsing–remitting multiple sclerosis (RRMS). METHODS: Brain volume changes were evaluated in 23 patients with RRMS treated with interferon β-1a 44 μg given subcutaneously (SC) three times a week (tiw) and 15 healthy controls. Percentages of whole bra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dwyer, Michael G., Zivadinov, Robert, Tao, Yazhong, Zhang, Xin, Kennedy, Cheryl, Bergsland, Niels, Ramasamy, Deepa P., Durfee, Jackie, Hojnacki, David, Weinstock-Guttman, Bianca, Hayward, Brooke, Dangond, Fernando, Markovic-Plese, Silva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642690/ https://www.ncbi.nlm.nih.gov/pubmed/26559139 http://dx.doi.org/10.1186/s12883-015-0488-9

Ejemplares similares

Immunologic and MRI markers of the therapeutic effect of IFN-β-1a in relapsing-remitting MS
por: Tao, Yazhong, et al.
Publicado: (2015)

Effect of Treatment with Interferon Beta-1a on Changes in Voxel-Wise Magnetization Transfer Ratio in Normal Appearing Brain Tissue and Lesions of Patients with Relapsing–Remitting Multiple Sclerosis: A 24-Week, Controlled Pilot Study
por: Zivadinov, Robert, et al.
Publicado: (2014)

Comparison of Standard 1.5 T vs. 3 T Optimized Protocols in Patients Treated with Glatiramer Acetate. A Serial MRI Pilot Study
por: Zivadinov, Robert, et al.
Publicado: (2012)

Clinical feasibility of longitudinal lateral ventricular volume measurements on T2-FLAIR across MRI scanner changes
por: Jakimovski, Dejan, et al.
Publicado: (2021)

Effect of Teriflunomide and Dimethyl Fumarate on Cortical Atrophy and Leptomeningeal Inflammation in Multiple Sclerosis: A Retrospective, Observational, Case-Control Pilot Study
por: Zivadinov, Robert, et al.
Publicado: (2019)

Serum Neurofilament Light Chain Levels are Associated with Lower Thalamic Perfusion in Multiple Sclerosis
por: Jakimovski, Dejan, et al.
Publicado: (2020)

Quantifying disease pathology and predicting disease progression in multiple sclerosis with only clinical routine T2-FLAIR MRI
por: Fuchs, Tom A., et al.
Publicado: (2021)

Neurological software tool for reliable atrophy measurement (NeuroSTREAM) of the lateral ventricles on clinical-quality T2-FLAIR MRI scans in multiple sclerosis
por: Dwyer, Michael G., et al.
Publicado: (2017)

Decreased brain venous vasculature visibility on susceptibility-weighted imaging venography in patients with multiple sclerosis is related to chronic cerebrospinal venous insufficiency
por: Zivadinov, Robert, et al.
Publicado: (2011)

Retinal Blood Vessel Analysis Using Optical Coherence Tomography (OCT) in Multiple Sclerosis
por: Young, Nicholas, et al.
Publicado: (2023)

Cortical and Deep Gray Matter Perfusion Associations With Physical and Cognitive Performance in Multiple Sclerosis Patients
por: Jakimovski, Dejan, et al.
Publicado: (2020)

Longitudinal analysis of cerebral aqueduct flow measures: multiple sclerosis flow changes driven by brain atrophy
por: Jakimovski, Dejan, et al.
Publicado: (2020)

Neuroimaging Correlates of Patient-Reported Outcomes in Multiple Sclerosis
por: Jakimovski, Dejan, et al.
Publicado: (2023)

Hypoperfusion of brain parenchyma is associated with the severity of chronic cerebrospinal venous insufficiency in patients with multiple sclerosis: a cross-sectional preliminary report
por: Zamboni, Paolo, et al.
Publicado: (2011)

Decreasing brain iron in multiple sclerosis: The difference between concentration and content in iron MRI
por: Schweser, Ferdinand, et al.
Publicado: (2020)

Relationships Among Circulating Levels of Hemostasis Inhibitors, Chemokines, Adhesion Molecules, and MRI Characteristics in Multiple Sclerosis
por: Ziliotto, Nicole, et al.
Publicado: (2020)

Increased contrast enhancing lesion activity in relapsing–remitting multiple sclerosis migraine patients()
por: Graziano, Elliot, et al.
Publicado: (2015)

Iron-related gene variants and brain iron in multiple sclerosis and healthy individuals
por: Hagemeier, Jesper, et al.
Publicado: (2017)

Reserve-related activities and MRI metrics in multiple sclerosis patients and healthy controls: an observational study
por: Schwartz, Carolyn E., et al.
Publicado: (2016)

MRI segmentation analysis in temporal lobe and idiopathic generalized epilepsy
por: Goldberg, Hila, et al.
Publicado: (2014)

Serum lipid profiles are associated with disability and MRI outcomes in multiple sclerosis
por: Weinstock-Guttman, Bianca, et al.
Publicado: (2011)

Proteomics and relationship with axonal pathology in multiple sclerosis: 5-year diffusion tensor imaging study
por: Jakimovski, Dejan, et al.
Publicado: (2023)

Preserved network functional connectivity underlies cognitive reserve in multiple sclerosis
por: Fuchs, Tom A., et al.
Publicado: (2019)

Changes of deep gray matter magnetic susceptibility over 2 years in multiple sclerosis and healthy control brain
por: Hagemeier, Jesper, et al.
Publicado: (2017)

Humoral response to EBV is associated with cortical atrophy and lesion burden in patients with MS
por: Zivadinov, Robert, et al.
Publicado: (2016)

Improved assessment of multiple sclerosis lesion segmentation agreement via detection and outline error estimates
por: Wack, David S, et al.
Publicado: (2012)

Activated IL-1RI Signaling Pathway Induces Th17 Cell Differentiation via Interferon Regulatory Factor 4 Signaling in Patients with Relapsing-Remitting Multiple Sclerosis
por: Sha, Yonggang, et al.
Publicado: (2016)

Detecting isolated cognitive relapses in persons with MS
por: Morrow, Sarah A, et al.
Publicado: (2023)

Infections, Vaccines and Autoimmunity: A Multiple Sclerosis Perspective
por: Jakimovski, Dejan, et al.
Publicado: (2020)

Comparative injection-site pain and tolerability of subcutaneous serum-free formulation of interferonβ-1a versus subcutaneous interferonβ-1b: results of the randomized, multicenter, Phase IIIb REFORMS study
por: Singer, Barry, et al.
Publicado: (2012)

Improved operator agreement and efficiency using the minimum area contour change method for delineation of hyperintense multiple sclerosis lesions on FLAIR MRI
por: Wack, David S, et al.
Publicado: (2013)

Risk Factors for Chronic Cerebrospinal Venous Insufficiency (CCSVI) in a Large Cohort of Volunteers
por: Dolic, Kresimir, et al.
Publicado: (2011)

Chronic cerebrospinal venous insufficiency is not associated with cognitive impairment in multiple sclerosis
por: Benedict, Ralph HB, et al.
Publicado: (2013)

An Observational Study to Assess Brain MRI Change and Disease Progression in Multiple Sclerosis Clinical Practice—The MS‐MRIUS Study
por: Zivadinov, Robert, et al.
Publicado: (2016)

Iron deposition and inflammation in multiple sclerosis. Which one comes first?
por: Zivadinov, Robert, et al.
Publicado: (2011)

Brain atrophy and lesion burden are associated with disability progression in a multiple sclerosis real-world dataset using only T2-FLAIR: The NeuroSTREAM MSBase study
por: Barnett, Michael, et al.
Publicado: (2021)

No association between variations in extracranial venous anatomy and clinical outcomes in multiple sclerosis patients over 5 years
por: Gandhi, Sirin, et al.
Publicado: (2019)

Bimonthly Evolution of Cortical Atrophy in Early Relapsing-Remitting Multiple Sclerosis over 2 Years: A Longitudinal Study
por: Zivadinov, Robert, et al.
Publicado: (2013)

Multimodal noninvasive and invasive imaging of extracranial venous abnormalities indicative of CCSVI: Results of the PREMiSe pilot study
por: Zivadinov, Robert, et al.
Publicado: (2013)

Reserve-building activities in multiple sclerosis patients and healthy controls: a descriptive study
por: Schwartz, Carolyn E., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_1g5am4f6g3neg59dsjd4covpfm