A novel neuroferritinopathy mouse model (FTL 498InsTC) shows progressive brain iron dysregulation, morphological signs of early neurodegeneration and motor coordination deficits

Neuroferritinopathy is a rare genetic disease with a dominant autosomal transmission caused by mutations of the ferritin light chain gene (FTL). It belongs to Neurodegeneration with Brain Iron Accumulation, a group of disorders where iron dysregulation is tightly associated with neurodegeneration. W...

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Detalles Bibliográficos
Autores principales: Maccarinelli, Federica, Pagani, Antonella, Cozzi, Anna, Codazzi, Franca, Di Giacomo, Giuseppina, Capoccia, Sara, Rapino, Stefania, Finazzi, Dario, Politi, Letterio Salvatore, Cirulli, Francesca, Giorgio, Marco, Cremona, Ottavio, Grohovaz, Fabio, Levi, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642750/
https://www.ncbi.nlm.nih.gov/pubmed/25447222
http://dx.doi.org/10.1016/j.nbd.2014.10.023

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