Expression of Interferon Lambda 4 Is Associated with Reduced Proliferation and Increased Cell Death in Human Hepatic Cells

Interferon lambda 4 (IFN-λ4) is a novel type-III interferon that can be generated only in individuals carrying a ΔG frame-shift allele of an exonic genetic variant (rs368234815-ΔG/TT). The rs368234815-ΔG allele is strongly associated with decreased clearance of hepatitis C virus (HCV) infection. Her...

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Detalles Bibliográficos
Autores principales: Onabajo, Olusegun O., Porter-Gill, Patricia, Paquin, Ashley, Rao, Nina, Liu, Luyang, Tang, Wei, Brand, Nathan, Prokunina-Olsson, Ludmila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2015
Materias:
Research Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642834/
https://www.ncbi.nlm.nih.gov/pubmed/26134097
http://dx.doi.org/10.1089/jir.2014.0161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642834/
https://www.ncbi.nlm.nih.gov/pubmed/26134097
http://dx.doi.org/10.1089/jir.2014.0161

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