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ARF-GEF cytohesin-2/ARNO regulates R-Ras and α5-integrin recycling through an EHD1-positive compartment

When expressed in epithelial cells, cytohesin-2/ARNO, a guanine nucleotide exchange factor (GEF) for ARF small GTPases, causes a robust migration response. Recent evidence suggests that cytohesin-2/ARNO acts downstream of small the GTPase R-Ras to promote spreading and migration. We hypothesized tha...

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Detalles Bibliográficos
Autores principales:	Salem, Joseph C., Reviriego-Mendoza, Marta M., Santy, Lorraine C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642859/ https://www.ncbi.nlm.nih.gov/pubmed/26378252 http://dx.doi.org/10.1091/mbc.E15-05-0278

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