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Calibrating the Human Mutation Rate via Ancestral Recombination Density in Diploid Genomes
The human mutation rate is an essential parameter for studying the evolution of our species, interpreting present-day genetic variation, and understanding the incidence of genetic disease. Nevertheless, our current estimates of the rate are uncertain. Most notably, recent approaches based on countin...
Autores principales: | Lipson, Mark, Loh, Po-Ru, Sankararaman, Sriram, Patterson, Nick, Berger, Bonnie, Reich, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642934/ https://www.ncbi.nlm.nih.gov/pubmed/26562831 http://dx.doi.org/10.1371/journal.pgen.1005550 |
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