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Performance of Droplet Digital PCR in Non-Invasive Fetal RHD Genotyping - Comparison with a Routine Real-Time PCR Based Approach

Detection and characterization of circulating cell-free fetal DNA (cffDNA) from maternal circulation requires an extremely sensitive and precise method due to very low cffDNA concentration. In our study, droplet digital PCR (ddPCR) was implemented for fetal RHD genotyping from maternal plasma to com...

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Detalles Bibliográficos
Autores principales: Svobodová, Iveta, Pazourková, Eva, Hořínek, Aleš, Novotná, Michaela, Calda, Pavel, Korabečná, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642940/
https://www.ncbi.nlm.nih.gov/pubmed/26562517
http://dx.doi.org/10.1371/journal.pone.0142572