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Performance of Droplet Digital PCR in Non-Invasive Fetal RHD Genotyping - Comparison with a Routine Real-Time PCR Based Approach
Detection and characterization of circulating cell-free fetal DNA (cffDNA) from maternal circulation requires an extremely sensitive and precise method due to very low cffDNA concentration. In our study, droplet digital PCR (ddPCR) was implemented for fetal RHD genotyping from maternal plasma to com...
Autores principales: | Svobodová, Iveta, Pazourková, Eva, Hořínek, Aleš, Novotná, Michaela, Calda, Pavel, Korabečná, Marie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642940/ https://www.ncbi.nlm.nih.gov/pubmed/26562517 http://dx.doi.org/10.1371/journal.pone.0142572 |
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