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The intellectual disability gene Kirrel3 regulates target-specific mossy fiber synapse development in the hippocampus

Synaptic target specificity, whereby neurons make distinct types of synapses with different target cells, is critical for brain function, yet the mechanisms driving it are poorly understood. In this study, we demonstrate Kirrel3 regulates target-specific synapse formation at hippocampal mossy fiber...

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Detalles Bibliográficos
Autores principales: Martin, E Anne, Muralidhar, Shruti, Wang, Zhirong, Cervantes, Diégo Cordero, Basu, Raunak, Taylor, Matthew R, Hunter, Jennifer, Cutforth, Tyler, Wilke, Scott A, Ghosh, Anirvan, Williams, Megan E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642954/
https://www.ncbi.nlm.nih.gov/pubmed/26575286
http://dx.doi.org/10.7554/eLife.09395