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The intellectual disability gene Kirrel3 regulates target-specific mossy fiber synapse development in the hippocampus
Synaptic target specificity, whereby neurons make distinct types of synapses with different target cells, is critical for brain function, yet the mechanisms driving it are poorly understood. In this study, we demonstrate Kirrel3 regulates target-specific synapse formation at hippocampal mossy fiber...
Autores principales: | Martin, E Anne, Muralidhar, Shruti, Wang, Zhirong, Cervantes, Diégo Cordero, Basu, Raunak, Taylor, Matthew R, Hunter, Jennifer, Cutforth, Tyler, Wilke, Scott A, Ghosh, Anirvan, Williams, Megan E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642954/ https://www.ncbi.nlm.nih.gov/pubmed/26575286 http://dx.doi.org/10.7554/eLife.09395 |
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