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Notch1 Pathway Activity Determines the Regulatory Role of Cancer-Associated Fibroblasts in Melanoma Growth and Invasion

Cancer-associated fibroblasts (CAF) play a crucial role in regulating cancer progression, yet the molecular determinant that governs the tumor regulatory role of CAF remains unknown. Using a mouse melanoma model in which exogenous melanoma cells were grafted on the skin of two lines of mice where th...

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Detalles Bibliográficos
Autores principales:	Shao, Hongwei, Kong, Ranran, Ferrari, Massimiliano L., Radtke, Freddy, Capobianco, Anthony J., Liu, Zhao-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643021/ https://www.ncbi.nlm.nih.gov/pubmed/26562315 http://dx.doi.org/10.1371/journal.pone.0142815

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