Cargando…

Candida albicans Targets a Lipid Raft/Dectin-1 Platform to Enter Human Monocytes and Induce Antigen Specific T Cell Responses

Several pathogens have been described to enter host cells via cholesterol-enriched membrane lipid raft microdomains. We found that disruption of lipid rafts by the cholesterol-extracting agent methyl-β-cyclodextrin or by the cholesterol-binding antifungal drug Amphotericin B strongly impairs the upt...

Descripción completa

Detalles Bibliográficos
Autores principales:	de Turris, Valeria, Teloni, Raffaela, Chiani, Paola, Bromuro, Carla, Mariotti, Sabrina, Pardini, Manuela, Nisini, Roberto, Torosantucci, Antonella, Gagliardi, Maria Cristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643028/ https://www.ncbi.nlm.nih.gov/pubmed/26562838 http://dx.doi.org/10.1371/journal.pone.0142531

Ejemplares similares

Antibodies against a β-glucan-protein complex of Candida albicans and its potential as indicator of protective immunity in candidemic patients
por: Torosantucci, Antonella, et al.
Publicado: (2017)

Optimised production of an anti-fungal antibody in Solanaceae hairy roots to develop new formulations against Candida albicans
por: Catellani, Marcello, et al.
Publicado: (2020)

A Murine, Bispecific Monoclonal Antibody Simultaneously Recognizing β-Glucan and MP65 Determinants in Candida Species
por: Zito, Andrea, et al.
Publicado: (2016)

Cytometric detection of antigen-specific IFN-γ/IL-2 secreting cells in the diagnosis of tuberculosis
por: Sargentini, Valeria, et al.
Publicado: (2009)

Differential Adaptation of Candida albicans In Vivo Modulates Immune Recognition by Dectin-1
por: Marakalala, Mohlopheni J., et al.
Publicado: (2013)

Dectin-1-Mediated DC-SIGN Recruitment to Candida albicans Contact Sites
por: Choraghe, Rohan P., et al.
Publicado: (2021)

Correction: Differential Adaptation of Candida albicans In Vivo Modulates Immune Recognition by Dectin-1
por: Marakalala, Mohlopheni J., et al.
Publicado: (2013)

Anion Exchanger 2 Regulates Dectin-1-Dependent Phagocytosis and Killing of Candida albicans
por: Urso, Katia, et al.
Publicado: (2016)

Dectin-1 Facilitates IL-18 Production for the Generation of Protective Antibodies Against Candida albicans
por: Shen, Hui, et al.
Publicado: (2020)

Candida albicans triggers NADPH oxidase-independent neutrophil extracellular traps through dectin-2
por: Wu, Sheng-Yang, et al.
Publicado: (2019)

PPARγ Controls Dectin-1 Expression Required for Host Antifungal Defense against Candida albicans
por: Galès, Amandine, et al.
Publicado: (2010)

MBL-Mediated Opsonophagocytosis of Candida albicans by Human Neutrophils Is Coupled with Intracellular Dectin-1-Triggered ROS Production
por: Li, Dongsheng, et al.
Publicado: (2012)

Bruton's Tyrosine Kinase (BTK) and Vav1 Contribute to Dectin1-Dependent Phagocytosis of Candida albicans in Macrophages
por: Strijbis, Karin, et al.
Publicado: (2013)

A novel glyco-conjugate vaccine against fungal pathogens
por: Torosantucci, Antonella, et al.
Publicado: (2005)

Protection by Anti-β-Glucan Antibodies Is Associated with Restricted β-1,3 Glucan Binding Specificity and Inhibition of Fungal Growth and Adherence
por: Torosantucci, Antonella, et al.
Publicado: (2009)

Differential Dependencies of Monocytes and Neutrophils on Dectin-1, Dectin-2 and Complement for the Recognition of Fungal Particles in Inflammation
por: McDonald, Jacqueline U., et al.
Publicado: (2012)

Dependence on Dectin-1 Varies With Multiple Candida Species
por: Thompson, Aiysha, et al.
Publicado: (2019)

The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans
por: Cheng, Shih-Chin, et al.
Publicado: (2011)

Proteomic Analysis of Rta2p-Dependent Raft-Association of Detergent-Resistant Membranes in Candida albicans
por: Wang, Lin, et al.
Publicado: (2012)

Kangbainian Lotion Ameliorates Vulvovaginal Candidiasis in Mice by Inhibiting the Growth of Fluconazole-Resistant Candida albicans and the Dectin-1 Signaling Pathway Activation
por: Chen, Zewei, et al.
Publicado: (2022)

Zika Virus Exploits Lipid Rafts to Infect Host Cells
por: Peruzzu, Daniela, et al.
Publicado: (2022)

IL-34 Suppresses Candida albicans Induced TNFα Production in M1 Macrophages by Downregulating Expression of Dectin-1 and TLR2
por: Xu, Rong, et al.
Publicado: (2015)

Mnn10 Maintains Pathogenicity in Candida albicans by Extending α-1,6-Mannose Backbone to Evade Host Dectin-1 Mediated Antifungal Immunity
por: Zhang, Shi Qun, et al.
Publicado: (2016)

Reduced PICD in Monocytes Mounts Altered Neonate Immune Response to Candida albicans
por: Dreschers, Stephan, et al.
Publicado: (2016)

The Plant Defensin NaD1 Enters the Cytoplasm of Candida albicans via Endocytosis
por: Hayes, Brigitte M. E., et al.
Publicado: (2018)

Role of Dectin-2 for Host Defense against Systemic Infection with Candida glabrata
por: Ifrim, Daniela C., et al.
Publicado: (2014)

The ATP Transporter VNUT Mediates Induction of Dectin-1-Triggered Candida Nociception
por: Maruyama, Kenta, et al.
Publicado: (2018)

Modulatory role of vitamin A on the Candida albicans-induced immune response in human monocytes
por: Klassert, Tilman E., et al.
Publicado: (2014)

Candida albicans β-Glucan Differentiates Human Monocytes Into a Specific Subset of Macrophages
por: Leonhardt, Julia, et al.
Publicado: (2018)

Multi-species biofilm of Candida albicans and non-Candida albicans Candida species on acrylic substrate
por: K PATHAK, Apurva, et al.
Publicado: (2012)

Candida albicans-enteric viral interactions—The prostaglandin E(2) connection and host immune responses
por: Mochochoko, Bonang M., et al.
Publicado: (2022)

Candidalysin Is the Hemolytic Factor of Candida albicans
por: Mogavero, Selene, et al.
Publicado: (2022)

Dependence on Mincle and Dectin-2 Varies With Multiple Candida Species During Systemic Infection
por: Thompson, Aiysha, et al.
Publicado: (2021)

Candida albicans versus Candida dubliniensis: Why Is C. albicans More Pathogenic?
por: Moran, Gary P., et al.
Publicado: (2012)

Azole Antifungal Resistance in Candida albicans and Emerging Non-albicans Candida Species
por: Whaley, Sarah G., et al.
Publicado: (2017)

Erratum to: Modulatory role of vitamin A on the Candida albicans-induced immune response in human monocytes
por: Klassert, Tilman E., et al.
Publicado: (2014)

The Lipid Raft-Associated Protein Stomatin Is Required for Accumulation of Dectin-1 in the Phagosomal Membrane and for Full Activity of Macrophages against Aspergillus fumigatus
por: Goldmann, Marie, et al.
Publicado: (2023)

Pathogenesis and Virulence of Candida albicans and Candida glabrata
por: Henriques, Mariana, et al.
Publicado: (2020)

Phosphate in Virulence of Candida albicans and Candida glabrata
por: Köhler, Julia R., et al.
Publicado: (2020)

Risk factors for fatal candidemia caused by Candida albicans and non-albicans Candida species
por: Cheng, Ming-Fang, et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_l4mfr84hft8u9o28hjsfrgcp2f