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Fimasartan, a Novel Angiotensin-Receptor Blocker, Protects against Renal Inflammation and Fibrosis in Mice with Unilateral Ureteral Obstruction: the Possible Role of Nrf2
Objectives: A newly developed angiotensin II receptor blocker, fimasartan, is effective in lowering blood pressure through its action on the renin-angiotensin system. Renal interstitial fibrosis, believed to be due to oxidative injury, is an end-stage process in the progression of chronic kidney dis...
Autores principales: | Kim, Soojeong, Kim, Sung Jun, Yoon, Hye Eun, Chung, Sungjin, Choi, Bum Soon, Park, Cheol Whee, Shin, Seok Joon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643080/ https://www.ncbi.nlm.nih.gov/pubmed/26640409 http://dx.doi.org/10.7150/ijms.13187 |
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