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Differentiation of human ESCs to retinal ganglion cells using a CRISPR engineered reporter cell line

Retinal ganglion cell (RGC) injury and cell death from glaucoma and other forms of optic nerve disease is a major cause of irreversible vision loss and blindness. Human pluripotent stem cell (hPSC)-derived RGCs could provide a source of cells for the development of novel therapeutic molecules as wel...

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Detalles Bibliográficos
Autores principales:	Sluch, Valentin M., Davis, Chung-ha O., Ranganathan, Vinod, Kerr, Justin M., Krick, Kellin, Martin, Russ, Berlinicke, Cynthia A., Marsh-Armstrong, Nicholas, Diamond, Jeffrey S., Mao, Hai-Quan, Zack, Donald J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643248/ https://www.ncbi.nlm.nih.gov/pubmed/26563826 http://dx.doi.org/10.1038/srep16595

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