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Activin A/BMP2 chimera AB235 drives efficient redifferentiation of long term cultured autologous chondrocytes
Autologous chondrocyte implantation (ACI) depends on the quality and quantity of implanted cells and is hindered by the fact that chondrocytes cultured for long periods of time undergo dedifferentiation. Here we have developed a reproducible and efficient chondrogenic protocol to redifferentiate cho...
Autores principales: | Jiménez, G., López-Ruiz, E., Kwiatkowski, W., Montañez, E., Arrebola, F., Carrillo, E., Gray, P. C., Belmonte, J. C. Izpisua, Choe, S., Perán, M., Marchal, J. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643338/ https://www.ncbi.nlm.nih.gov/pubmed/26563344 http://dx.doi.org/10.1038/srep16400 |
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