Local 3D matrix microenvironment regulates cell migration through spatiotemporal dynamics of contractility-dependent adhesions

The physical properties of two-dimensional (2D) extracellular matrices (ECMs) modulate cell adhesion dynamics and motility, but little is known about the roles of local microenvironmental differences in three-dimensional (3D) ECMs. Here we generate 3D collagen gels of varying matrix microarchitectur...

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Detalles Bibliográficos
Autores principales: Doyle, Andrew D., Carvajal, Nicole, Jin, Albert, Matsumoto, Kazue, Yamada, Kenneth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643399/
https://www.ncbi.nlm.nih.gov/pubmed/26548801
http://dx.doi.org/10.1038/ncomms9720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643399/
https://www.ncbi.nlm.nih.gov/pubmed/26548801
http://dx.doi.org/10.1038/ncomms9720

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