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Cis-regulatory mechanisms governing stem and progenitor cell transitions
Cis-element encyclopedias provide information on phenotypic diversity and disease mechanisms. Although cis-element polymorphisms and mutations are instructive, deciphering function remains challenging. Mutation of an intronic GATA motif (+9.5) in GATA2, encoding a master regulator of hematopoiesis,...
Autores principales: | Johnson, Kirby D., Kong, Guangyao, Gao, Xin, Chang, Yuan-I, Hewitt, Kyle J., Sanalkumar, Rajendran, Prathibha, Rajalekshmi, Ranheim, Erik A., Dewey, Colin N., Zhang, Jing, Bresnick, Emery H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643771/ https://www.ncbi.nlm.nih.gov/pubmed/26601269 http://dx.doi.org/10.1126/sciadv.1500503 |
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