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Transcriptional regulation of APOBEC3 antiviral immunity through the CBF-β/RUNX axis

A diverse set of innate immune mechanisms protects cells from viral infections. The APOBEC3 family of DNA cytosine deaminases is an integral part of these defenses. For instance, APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H would have the potential to destroy HIV-1 complementary DNA replication interm...

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Detalles Bibliográficos
Autores principales:	Anderson, Brett D., Harris, Reuben S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643775/ https://www.ncbi.nlm.nih.gov/pubmed/26601257 http://dx.doi.org/10.1126/sciadv.1500296

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