Endogenous Murine BST-2/Tetherin Is Not a Major Restriction Factor of Influenza A Virus Infection

BST-2 (tetherin, CD317, HM1.24) restricts virus growth by tethering enveloped viruses to the cell surface. The role of BST-2 during influenza A virus infection (IAV) is controversial. Here, we assessed the capacity of endogenous BST-2 to restrict IAV in primary murine cells. IAV infection increased...

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Detalles Bibliográficos
Autores principales: Londrigan, Sarah L., Tate, Michelle D., Job, Emma R., Moffat, Jessica M., Wakim, Linda M., Gonelli, Christopher A., Purcell, Damien F. J., Brooks, Andrew G., Villadangos, Jose A., Reading, Patrick C., Mintern, Justine D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643895/
https://www.ncbi.nlm.nih.gov/pubmed/26566124
http://dx.doi.org/10.1371/journal.pone.0142925

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