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Blastomycosis in northwestern Ontario, 2004 to 2014

Blastomycosis is an invasive fungal disease caused by Blastomyces dermatitidis and the recently discovered Blastomyces gilchristii. The medical charts of 64 patients with confirmed cases of blastomycosis in northwestern Ontario during a 10-year period (2004 to 2014) were retrospectively reviewed. Th...

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Detalles Bibliográficos
Autores principales: Dalcin, Daniel, Ahmed, Syed Zaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pulsus Group Inc 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644009/
https://www.ncbi.nlm.nih.gov/pubmed/26600814
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author Dalcin, Daniel
Ahmed, Syed Zaki
author_facet Dalcin, Daniel
Ahmed, Syed Zaki
author_sort Dalcin, Daniel
collection PubMed
description Blastomycosis is an invasive fungal disease caused by Blastomyces dermatitidis and the recently discovered Blastomyces gilchristii. The medical charts of 64 patients with confirmed cases of blastomycosis in northwestern Ontario during a 10-year period (2004 to 2014) were retrospectively reviewed. The number of patients diagnosed with blastomycosis in Ontario was observed to have increased substantially compared with before 1990, when blastomycosis was removed from the list of reportable diseases. Aboriginals were observed to be disproportionately represented in the patient population. Of the patients whose smoking status was known, 71.4% had a history of smoking. 59.4% of patients had underlying comorbidities and a higher comorbidity rate was observed among Aboriginal patients. The case-fatality rate from direct complications of blastomycosis disease was calculated to be 20.3%; this case-fatality rate is the highest ever to be reported in Canada and more than double that of previously published Canadian studies. The clinical characteristics of 64 patients diagnosed with blastomycosis are summarized.
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spelling pubmed-46440092015-11-23 Blastomycosis in northwestern Ontario, 2004 to 2014 Dalcin, Daniel Ahmed, Syed Zaki Can J Infect Dis Med Microbiol Original Article Blastomycosis is an invasive fungal disease caused by Blastomyces dermatitidis and the recently discovered Blastomyces gilchristii. The medical charts of 64 patients with confirmed cases of blastomycosis in northwestern Ontario during a 10-year period (2004 to 2014) were retrospectively reviewed. The number of patients diagnosed with blastomycosis in Ontario was observed to have increased substantially compared with before 1990, when blastomycosis was removed from the list of reportable diseases. Aboriginals were observed to be disproportionately represented in the patient population. Of the patients whose smoking status was known, 71.4% had a history of smoking. 59.4% of patients had underlying comorbidities and a higher comorbidity rate was observed among Aboriginal patients. The case-fatality rate from direct complications of blastomycosis disease was calculated to be 20.3%; this case-fatality rate is the highest ever to be reported in Canada and more than double that of previously published Canadian studies. The clinical characteristics of 64 patients diagnosed with blastomycosis are summarized. Pulsus Group Inc 2015 /pmc/articles/PMC4644009/ /pubmed/26600814 Text en Copyright© 2015 Pulsus Group Inc. All rights reserved This open-access article is distributed under the terms of the Creative Commons Attribution Non-Commercial License (CC BY-NC) (http://creativecommons.org/licenses/by-nc/4.0/), which permits reuse, distribution and reproduction of the article, provided that the original work is properly cited and the reuse is restricted to noncommercial purposes. For commercial reuse, contact reprints@pulsus.com
spellingShingle Original Article
Dalcin, Daniel
Ahmed, Syed Zaki
Blastomycosis in northwestern Ontario, 2004 to 2014
title Blastomycosis in northwestern Ontario, 2004 to 2014
title_full Blastomycosis in northwestern Ontario, 2004 to 2014
title_fullStr Blastomycosis in northwestern Ontario, 2004 to 2014
title_full_unstemmed Blastomycosis in northwestern Ontario, 2004 to 2014
title_short Blastomycosis in northwestern Ontario, 2004 to 2014
title_sort blastomycosis in northwestern ontario, 2004 to 2014
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644009/
https://www.ncbi.nlm.nih.gov/pubmed/26600814
work_keys_str_mv AT dalcindaniel blastomycosisinnorthwesternontario2004to2014
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