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Trinitrotoluene Induces Endoplasmic Reticulum Stress and Apoptosis in HePG2 Cells

BACKGROUND: This study aims to describe trinitrotoluene (TNT)-induced endoplasmic reticulum stress (ERS) and apoptosis in HePG2 cells. MATERIAL/METHODS: HePG2 cells were cultured in vitro with 0, 6, 12, or 24 μg/ml TNT solution for 12, 24, and 48 h. Western blotting was performed to detect intracell...

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Detalles Bibliográficos
Autores principales: Song, Li, Wang, Yue, Wang, Jun, Yang, Fan, Li, Xiaojun, Wu, Yonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644021/
https://www.ncbi.nlm.nih.gov/pubmed/26551326
http://dx.doi.org/10.12659/MSM.894169