Influence of CCND1 G870A polymorphism on the risk of HBV-related HCC and cyclin D1 splicing variant expression in Chinese population

The G870A polymorphism in the exon 4/intron 4 boundary of CCND1 gene is thought to influence the generation of two mRNAs (cyclin D1a and cyclin D1b). The “A” allele codes for a truncated variant, cyclin D1b, which may have higher transforming activity. Herein, the tumor relevance of G870A polymorphi...

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Detalles Bibliográficos
Autores principales: Zeng, Zhenzhen, Tu, Jing, Cheng, Jin, Yao, Mingjie, Wu, Yali, Huang, Xiangbo, Xie, Xiaomeng, Zhang, Xiaolei, Lu, Fengmin, Chen, Xiangmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644212/
https://www.ncbi.nlm.nih.gov/pubmed/25851350
http://dx.doi.org/10.1007/s13277-015-3401-7

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