RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics

Tumor-educated blood platelets (TEPs) are implicated as central players in the systemic and local responses to tumor growth, thereby altering their RNA profile. We determined the diagnostic potential of TEPs by mRNA sequencing of 283 platelet samples. We distinguished 228 patients with localized and...

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Detalles Bibliográficos
Autores principales: Best, Myron G., Sol, Nik, Kooi, Irsan, Tannous, Jihane, Westerman, Bart A., Rustenburg, François, Schellen, Pepijn, Verschueren, Heleen, Post, Edward, Koster, Jan, Ylstra, Bauke, Ameziane, Najim, Dorsman, Josephine, Smit, Egbert F., Verheul, Henk M., Noske, David P., Reijneveld, Jaap C., Nilsson, R. Jonas A., Tannous, Bakhos A., Wesseling, Pieter, Wurdinger, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644263/
https://www.ncbi.nlm.nih.gov/pubmed/26525104
http://dx.doi.org/10.1016/j.ccell.2015.09.018

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