Integrating tumor microenvironment with cancer molecular classifications

The composition of the tumor microenvironment is associated with a patient's prognosis and can be therapeutically targeted. A link between the cellular composition and genomic features of the tumor and its response to immunotherapy is beginning to emerge. Analyzing the microenvironment of tumor...

Descripción completa

Detalles Bibliográficos
Autores principales: Becht, Etienne, de Reyniès, Aurélien, Fridman, Wolf H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644274/
https://www.ncbi.nlm.nih.gov/pubmed/26568192
http://dx.doi.org/10.1186/s13073-015-0241-4
_version_ 1782400645887688704
author Becht, Etienne
de Reyniès, Aurélien
Fridman, Wolf H.
author_facet Becht, Etienne
de Reyniès, Aurélien
Fridman, Wolf H.
author_sort Becht, Etienne
collection PubMed
description The composition of the tumor microenvironment is associated with a patient's prognosis and can be therapeutically targeted. A link between the cellular composition and genomic features of the tumor and its response to immunotherapy is beginning to emerge. Analyzing the microenvironment of tumor molecular subgroups can be a useful approach to tailor immunotherapies.
format Online
Article
Text
id pubmed-4644274
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-46442742015-11-15 Integrating tumor microenvironment with cancer molecular classifications Becht, Etienne de Reyniès, Aurélien Fridman, Wolf H. Genome Med Comment The composition of the tumor microenvironment is associated with a patient's prognosis and can be therapeutically targeted. A link between the cellular composition and genomic features of the tumor and its response to immunotherapy is beginning to emerge. Analyzing the microenvironment of tumor molecular subgroups can be a useful approach to tailor immunotherapies. BioMed Central 2015-11-14 /pmc/articles/PMC4644274/ /pubmed/26568192 http://dx.doi.org/10.1186/s13073-015-0241-4 Text en © Becht et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Comment
Becht, Etienne
de Reyniès, Aurélien
Fridman, Wolf H.
Integrating tumor microenvironment with cancer molecular classifications
title Integrating tumor microenvironment with cancer molecular classifications
title_full Integrating tumor microenvironment with cancer molecular classifications
title_fullStr Integrating tumor microenvironment with cancer molecular classifications
title_full_unstemmed Integrating tumor microenvironment with cancer molecular classifications
title_short Integrating tumor microenvironment with cancer molecular classifications
title_sort integrating tumor microenvironment with cancer molecular classifications
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644274/
https://www.ncbi.nlm.nih.gov/pubmed/26568192
http://dx.doi.org/10.1186/s13073-015-0241-4
work_keys_str_mv AT bechtetienne integratingtumormicroenvironmentwithcancermolecularclassifications
AT dereyniesaurelien integratingtumormicroenvironmentwithcancermolecularclassifications
AT fridmanwolfh integratingtumormicroenvironmentwithcancermolecularclassifications

Ejemplares similares