Cargando…
Repeated treatment with bone marrow cell secretory products maintains long-term renoprotection in experimental chronic kidney disease: a placebo-controlled trial
BACKGROUND: Bone marrow-derived early outgrowth cells (EOCs) secrete soluble factors that exert potent renoprotective effects, such that infusion of their conditioned medium recapitulates the affects of the cells themselves. OBJECTIVES: The objective of this study is to test whether the protective e...
Autores principales: | Yuen, Darren A., Kepecs, David M., Zhang, Yanling, Advani, Suzanne, Thai, Kerri, Connelly, Kim A., Gilbert, Richard E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644292/ https://www.ncbi.nlm.nih.gov/pubmed/26568839 http://dx.doi.org/10.1186/s40697-015-0082-5 |
Ejemplares similares
-
Progenitor cell secretory products exert additive renoprotective effects when combined with ace inhibitors in experimental CKD
por: Kepecs, David M, et al.
Publicado: (2016) -
Early-Outgrowth Bone Marrow Cells Attenuate Renal Injury and Dysfunction via an Antioxidant Effect in a Mouse Model of Type 2 Diabetes
por: Zhang, Yanling, et al.
Publicado: (2012) -
Sodium-Glucose Linked Cotransporter-2 Inhibition Does Not Attenuate Disease Progression in the Rat Remnant Kidney Model of Chronic Kidney Disease
por: Zhang, Yanling, et al.
Publicado: (2016) -
Role of the eNOS-NO System in Regulating the Antiproteinuric Effects of VEGF Receptor 2 Inhibition in Diabetes
por: Advani, Andrew, et al.
Publicado: (2013) -
Culture-Modified Bone Marrow Cells Attenuate Cardiac and Renal Injury in a Chronic Kidney Disease Rat Model via a Novel Antifibrotic Mechanism
por: Yuen, Darren A., et al.
Publicado: (2010)