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Development of a therapy against metastatic bladder cancer using an interleukin-2 surface-modified MB49 bladder cancer stem cells vaccine

INTRODUCTION: In previous study the streptavidin interleukin-2 (SA-IL-2)-modified MB49 vaccine was effective against bladder cancer in a mouse model. However, a small portion of tumors regrew because the vaccine could not eliminate MB49 bladder cancer stem cells (MCSCs). Accordingly, we developed a...

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Detalles Bibliográficos
Autores principales:	Zhu, Yong-tong, Pang, Shi-yu, Lei, Cheng-yong, Luo, Yang, Chu, Qing-jun, Tan, Wan-long
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644293/ https://www.ncbi.nlm.nih.gov/pubmed/26566931 http://dx.doi.org/10.1186/s13287-015-0211-1

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