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Persistent androgen receptor addiction in castration-resistant prostate cancer

It is now understood that persistent activation of the androgen receptor (AR) signaling pathway often underlies the development of castration-resistant prostate cancer (CRPC). This realization led to renewed interest in targeting the AR and ultimately to the development of the potent next-generation...

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Detalles Bibliográficos
Autores principales: Schweizer, Michael T., Yu, Evan Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644296/
https://www.ncbi.nlm.nih.gov/pubmed/26566796
http://dx.doi.org/10.1186/s13045-015-0225-2