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Expression profiling of the ubiquitin conjugating enzyme UbcM2 in murine brain reveals modest age-dependent decreases in specific neurons

BACKGROUND: UbcM2 is a ubiquitin-conjugating enzyme with roles in the turnover of damaged and misfolded proteins, cell cycle progression, development, and regulation of the antioxidant transcription factor, Nrf2. Recent screens have identified binding partners of the enzyme that are associated with...

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Detalles Bibliográficos
Autores principales: Larabee, Chelsea M., Georgescu, Constantin, Wren, Jonathan D., Plafker, Scott M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644300/
https://www.ncbi.nlm.nih.gov/pubmed/26566974
http://dx.doi.org/10.1186/s12868-015-0194-y