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Transient receptor potential ankyrin 1 that is induced in dorsal root ganglion neurons contributes to acute cold hypersensitivity after oxaliplatin administration
BACKGROUND: Peripheral cold neuropathic pain is a serious side effect of oxaliplatin treatment. However, the mechanism of oxaliplatin-induced cold hyperalgesia is unknown. In the present study, we investigated the effects of oxaliplatin on transient receptor potential ankyrin 1 (TRPA1) in dorsal roo...
Autores principales: | Yamamoto, Ken, Chiba, Noriko, Chiba, Terumasa, Kambe, Toshie, Abe, Kenji, Kawakami, Kazuyoshi, Utsunomiya, Iku, Taguchi, Kyoji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644342/ https://www.ncbi.nlm.nih.gov/pubmed/26567040 http://dx.doi.org/10.1186/s12990-015-0072-8 |
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