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VEGF-C is required for intestinal lymphatic vessel maintenance and lipid absorption
Vascular endothelial growth factor C (VEGF-C) binding to its tyrosine kinase receptor VEGFR-3 drives lymphatic vessel growth during development and in pathological processes. Although the VEGF-C/VEGFR-3 pathway provides a target for treatment of cancer and lymphedema, the physiological functions of...
Autores principales: | Nurmi, Harri, Saharinen, Pipsa, Zarkada, Georgia, Zheng, Wei, Robciuc, Marius R, Alitalo, Kari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644375/ https://www.ncbi.nlm.nih.gov/pubmed/26459520 http://dx.doi.org/10.15252/emmm.201505731 |
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