Multiplexed Integrating Plasmids for Engineering of the Erythromycin Gene Cluster for Expression in Streptomyces spp. and Combinatorial Biosynthesis

Bacteria in the genus Streptomyces and its close relatives are prolific producers of secondary metabolites with antibiotic activity. Genome sequencing of these bacteria has revealed a rich source of potentially new antibiotic pathways, whose products have never been observed. Moreover, these new pat...

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Detalles Bibliográficos
Autores principales: Fayed, Bahgat, Ashford, David A., Hashem, Amal M., Amin, Magdy A., El Gazayerly, Omaima N., Gregory, Matthew A., Smith, Margaret C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644662/
https://www.ncbi.nlm.nih.gov/pubmed/26431970
http://dx.doi.org/10.1128/AEM.02403-15

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